Jie Luo, Ph.D.

Research Projects

• Mechanism of BefA Protein in Ameliorating Type 2 Diabetes Mellitus Complicated with Non-Alcoholic Fatty Liver Disease via the AMPK and SREBP1 Pathways

• Role and Mechanism of BefA Protein in Ameliorating Non-Alcoholic Fatty Liver Disease by Regulating the AMPK Pathway via the Gut-Liver Axis

• Effects of Lactic Acid Bacteria on Prefrontal Cortex Neuronal Development and Cognitive Function

Research Achievements

• Jie Luo; Yujie Cai; Chunjian Jia; Xinfeng Zhang; Qifa Huang; Jing Wei; Qi Chen; Tingtao Chen; BefA protein alleviates progression of non-alcoholic fatty liver disease by modulating the AMPK signaling pathway through the gut-liver axis. Int J Biol Macromol, 2025, 294.

• Jie Luo; Yilin Fang; Zhanghua Qi; Fengyang Cui; Hong Hu; Shengjie Li; Tingtao Chen; Hongyan Zhang; Administration of a Next-Generation Probiotic Escherichia coli Nissle 1917-GLP-1 Alleviates Diabetes in Mice With Type 1 and Type 2 Diabetes. Can J Infect Dis Med Microbiol, 2025.

• Jie Luo; Ping Li; Tingtao Chen; Vaginal Lactobacillus affects sperm motility and may mediate female infertility. Chinese Journal of Microecology, 2022, 34(12): 1457.

• Jie Luo, Hongfei Zhang, Jiachen Lu, ChaoLin Ma, Tingtao Chen. Antidiabetic effect of an engineered bacterium Lactobacillus plantarum-pMG36e -GLP-1 in monkey model. Synth Syst Biotechnol, 2021, 6: 272-282.

• Hong Hu; Jie Luo; Ying Liu; Hongyu Li; Rui Jin; Shengjie Li; Jing Wei; Hong Wei; Tingtao Chen; Improvement effect of a next-generation probiotic L. plantarum-pMG36e-GLP-1 on type 2 diabetes mellitus via the gut–pancreas–liver axis. Food Funct, 2023, 14: 3179-3195.