Huanhong Ji , Ph.D.

Research Project

• Molecular Mechanism of Vesicle Transport Mediated by Molecular Motor Myo5b and Actin Nucleation Factor Spire

Research Achievements

• Tai-Tian Xiong#, Yi-Ning Lu#, Jiabin Pan, Ning Zhang, Miao Wei, Gaoyan La, Huan-Hong Ji, Si-Qin Ge, Xiang-Dong Li* (2025). Identification of the locust proctolin receptor and design of proctolin analogs. Pest Manag Sci. 81(12):8106-8116.

• Lin-Lin Yao#, Wei-Dong Hou#, Yi Liang, Xiang-Dong Li, Huan-Hong Ji* (2024). Spire2 and Rab11a synergistically activate myosin-5b motor function. Biochem Biophys Res Commun. 703:149653.

• Ning Zhang, Shu-Jie Zhou, Huan-Hong Ji, Xiang-Dong Li* (2022). Effects of the IQ1 motif of Drosophila myosin-5 on the calcium interaction of calmodulin. Cell Calcium, 103:102549.

• Huan-Hong Ji, Michael Ostap* (2020). The regulatory protein 14-3-3β binds to the IQ motifs of myosin-IC independently of phosphorylation. Journal of Biological Chemistry, 295(12), 3749-3746. (Editors' Pick)

• Tong Ni, Min Yuan, Huan-Hong Ji, Guangfei Tang, Yun Chen, Zhonghua Ma, and Xiang-dong Li* (2020). Effects of Mutations in the Phenamacril-Binding Site of Fusarium Myosin-1 on Its Motor Function and Phenamacril Sensitivity. ACS Omega, 5(34), 21815–21823.

• Huan-Hong Ji#, Lin-Lin Yao#, Chang Liu, Xiang-dong Li* (2019). Regulation of Myosin-5b by Rab11a and the Rab11 family interacting protein 2. Bioscience Reports, 39, BSR20181252.

• Hai-Man Zhang, Huan-Hong Ji, Tong Ni, Rong-Na Ma, Aibing Wang, and Xiang-dong Li* (2017). Characterization of Blebbistatin Inhibition of Smooth Muscle Myosin and Nonmuscle Myosin-2. Biochemistry, 56(32), 4235–4243.

• Chengqi Zhang#, Yun Chen#, Yanni Yin#, Huan-Hong Ji, Won-Bo Shim, Yiping Hou, Mingguo Zhou, Xiang-dong Li, and Zhonghua Ma* (2015). A small molecule species-specifically inhibits Fusarium myosin I. Environmental Microbiology, 17(8): 2735-2746.

• Huan-Hong Ji, Hai-Man Zhang, Mei Shen, Lin-Lin Yao, Xiang-dong Li* (2015). The motor function of Drosophila melanogaster myosin-5 is activated by calcium and cargo-binding protein dRab11. Biochemical Journal, 469(1):135-144.

• Zekuan Lu, Xiao-Nan Ma, Hai-Man Zhang, Huan-Hong Ji, Hao Ding, Jie Zhang, Dan Luo, Yujie Sun and Xiang-dong Li* (2014). Mouse Myosin-19 is a Plus-end-directed, High-duty Ratio Molecular Motor. Journal of Biological Chemistry, 289: 18535-18548.