罗清

姓名：罗清

职务\职称：主管技师

系别：公共卫生学院-临床检验诊断学

研究方向：自身免疫与抗感染免疫

办公电话：0791-88692794

简介：2011年毕业于南昌大学临床检验诊断学获得硕士学位，现任南昌大学第一附属医院检验科免疫室组长、主管技师、硕士生导师，江西省中西医结合检验医学分会专业委员会委员。长期从事与医学检验相关的自身免疫和抗感染免疫的教学研研工作，主持国家级省级课题多项，以第一作者和通讯作者署名发表学术论文40余篇，参与2016年江西省科学技术进步奖二等奖一项。

论文、专著与专利 ：

1.Qing Luo#, Lulu Zeng#, Lingbing Zeng, Jiayue Rao, Lu Zhang, Yang Guo, Zikun Huang*, Junming Li*；《Expression and clinical significance of circular RNAs hsa_circ_0000175 and hsa_circ_0008410 in peripheral blood mononuclear cells from patients with rheumatoid arthritis》；Int J Mol Med. 2020 Apr;45(4):1203-1212. doi: 10.3892/ijmm.2020.4498.

2.Qing Luo#, Lu Zhang#, Le Fang, Biqi Fu, Yang Guo, Zikun Huang*, Junming Li*；《Circular RNAs hsa_circ_0000479 in peripheral blood mononuclear cells as novel biomarkers for systemic lupus erythematosus》；Autoimmunity. 2020 May;53(3):167-176. doi: 10.1080/08916934.2020.1728529.

3.Qing Luo#, Jiayue Rao#, Lu Zhang, Biqi Fu, Yang Guo, Zikun Huang*, Junming Li*；《The study of METTL14, ALKBH5, and YTHDF2 in peripheral blood mononuclear cells from systemic lupus erythematosus》；Mol Genet Genomic Med. 2020 Sep;8(9):e1298. doi: 10.1002/mgg3.1298.

4.Qing Luo#, Biqi Fu#, Lu Zhang, Yang Guo, Zikun Huang*, Junming Li*；《Decreased Peripheral Blood ALKBH5 Correlates with Markers of Autoimmune Response in Systemic Lupus Erythematosus》；Dis Markers. 2020 Jun 25;2020:8193895. doi: 10.1155/2020/8193895.

5.Qing Luo#, Yujie Gao#, Lu Zhang, Jiayue Rao, Yang Guo, Zikun Huang*, Junming Li*；《Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis》；Biomed Res Int. 2020 Aug 20;2020:5735279. doi: 10.1155/2020/5735279.

6.罗清，张露，黄自坤，李俊明*. CDC27基因在系统性红斑狼疮中的表达和临床意义. 安微医科大学学报，2020，55（2）：292-295.

7.罗清，黄自坤，张露，李俊明*.环状ＲNA hsa_circ_0002715在系统性红斑狼疮患者全血中的表达和意义.安微医科大学学报，2020，55（7）：1130-1136.

8.黄自坤，曾璐璐，罗清*.系统性红斑狼疮患者外周血NK 细胞TIM-3 表达和意义.免疫学杂志，36（3）：248-253.

9.Qing Luo#, Lu Zhang#, Xue Li, Biqi Fu, Yang Guo, Zikun Huang*, Junming Li*；《Identifcation of circular RNAs hsa_circ_0044235 and hsa_circ_0068367 as novel biomarkers for systemic lupus erythematosus》；Int J Mol Med. 2019 Oct;44(4):1462-1472. doi: 10.3892/ijmm.2019.4302.

10.Qing Luo#, Jun Liu#, Biqi Fu, Lu Zhang, Yang Guo, Zikun Huang*, Junming Li*；《Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid Arthritis》；Dis Markers. 2019 Oct 29;2019:2073139. doi: 10.1155/2019/2073139.

11.Qing Luo#, Xue Li#, Lu Zhang, Fangyi Yao, Zhen Deng, Cheng Qing, Rigu Su, Jianqing Xu, Yang Guo, Zikun Huang*, Junming Li*；《Serum PGLYRP-1 is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis》；Mol Med Rep. 2019 Jan;19(1):589-594. doi: 10.3892/mmr.2018.9632.

12.黄自坤,张露, 曾璐璐, 罗清*.环状RNA hsa_circ_104871在系统性红斑狼疮患者外周血单个核细胞中的表达和意义.安徽医科大学学报,2019, 54(12):1947-1951.

13.黄自坤, 黄清水, 李雪, 鞠北华, 罗清*.CD64在RA患者单核细胞中的表达及与TNF-α的相关性研究.安徽医科大学学报,2019, 54(2):281-286.

14.Q Luo#, L Zhang#, X Li, B Fu, Z Deng, C Qing, R Su, J Xu, Y Guo, Z Huang*, J Li*；《 Identification of circular RNAs hsa_circ_0044235 in peripheral blood as novel biomarkers for rheumatoid arthritis》；Clin Exp Immunol. 2018 Oct;194(1):118-124. doi: 10.1111/cei.13181.

15.Qing Luo#, Jianqing Ye#, Lulu Zeng, Zhongqin Luo, Zhen Deng, Xue Li, Yang Guo, Zikun Huang*, Junming Li*；《Elevated expression of PD-1 on T cells correlates with disease activity in rheumatoid arthritis》；Mol Med Rep. 2018 Feb;17(2):3297-3305. doi: 10.3892/mmr.2017.8204.

16.Qing Luo#, Xue Li#, Chuxin Xu, Lulu Zeng, Jianqing Ye, Yang Guo, Zikun Huang*, Junming Li*；《Integrative analysis of long non-coding RNAs and mRNA expression profiles in systemic lupus erythematosus》；Mol Med Rep. 2018 Mar;17(3):3489-3496. doi: 10.3892/mmr.2017.8344.

17.Qing Luo#, Pengcheng Xiao, Xue Li, Zhen Deng, Cheng Qing, Rigu Su, Jianqing Xu, Yang Guo, Zikun Huang*, Junming Li*；《Overexpression of CD64 on CD14++CD16- and CD14++CD16+ monocytes of rheumatoid arthritis patients correlates with disease activity》；Exp Ther Med. 2018 Sep;16(3):2703-2711. doi: 10.3892/etm.2018.6452.

18.Qing Luo#, Xue Li#, Biqi Fu, Lu Zhang, Zhen Deng, Cheng Qing, Rigu Su, Jianqing Xu, Yang Guo, Zikun Huang*, Junming Li* ；《Decreased expression of TIGIT in NK cells correlates negatively with disease activity in systemic lupus erythematosus》；Int J Clin Exp Pathol. 2018 May 1;11(5):2408-2418. eCollection 2018.

19.Zikun Huang#, Rigu Su#, Cheng Qing, Yiping Peng, Qing Luo*, Junming Li* ；《Plasma circular RNAs hsa_circ_0001953 and hsa_circ_0009024 as diagnostic biomarkers for active tuberculosis》；Front Microbiol. 2018 Aug 30;9:2010. doi:10.3389/fmicb.2018.02010.

20.Zikun Huang#, Rigu Su#, Fangyi Yao, Yiping Peng, Qing Luo*, Junming Li*；《Circulating circular RNAs hsa_circ_0001204 and hsa_circ_0001747 act as diagnostic biomarkers for active tuberculosis detection》；Int J Clin Exp Pathol. 2018 Feb 1;11(2):586-594. eCollection 2018.

21.Zi-Kun Huang#, Fang-Yi Yao#, Jian-Qing Xu, Zhen Deng, Ri-Gu Su, Yi-Ping Peng, Qing Luo*, Jun-Ming Li* ；《Microarray Expression Profile of Circular RNAs in Peripheral Blood Mononuclear Cells from Active Tuberculosis Patients》；Cell Physiol Biochem. 2018;45(3):1230-1240. doi: 10.1159/000487454.

22.黄自坤，李雪，邓桢，罗清*.类风湿关节炎外周血单核细胞亚群 CD64 表达及意义.中国免疫学杂志,2018, 34(1):77-83.

23.李雪, 黄自坤, 邓桢, 罗清*.系统性红斑狼疮患者外周血NK细胞TIGIT的表达和意义.免疫学杂志，2018，34(7)：607-611.

24. 黄自坤, 曾璐璐, 罗清*.系统性红斑狼疮外周血NK细胞PD-1的表达及意义.广东医学，2018, 39(22)：3324-3329.

25.黄自坤, 李雪, 罗清*.类风湿关节炎单核巨噬细胞极化表型分析及临床意义.安徽医科大学学报, 2018, 53(4):605-609.

26. 李雪, 罗清*.巨噬细胞极化在类风湿关节炎中的作用.生命科学,2018, 30(3):261-266.

27.Qing Luo#, Jianqing Ye#, Lulu Zeng, Xue Li, Le Fang, Beihua Ju, Zikun Huang*, Junming Li*；《Elevated expression of TIGIT on CD3+CD4+T cells correlates with disease activity in systemic lupus erythematosus》；Allergy Asthma Clin Immunol. 2017 Feb 28;13:15. doi: 10.1186/s13223-017-0188-7.

28.Qing Luo#, Chuxin Xu#, Xue Li, Lulu Zeng, Jianqing Ye, Yang Guo, Zikun Huang*, Junming Li*；《Comprehensive analysis of long non-coding RNA and mRNA expression profiles in rheumatoid arthritis》；Exp Ther Med. 2017 Dec;14(6):5965-5973. doi: 10.3892/etm.2017.5284.

29.Qing Luo#, Zhen Deng#, Chuxin Xu, Lulu Zeng, Jianqing Ye, Xue Li, Yang Guo, Zikun Huang*, Junming Li*；《Elevated Expression of Immunoreceptor Tyrosine-Based Inhibitory Motif (TIGIT) on T Lymphocytes is Correlated with Disease Activity in Rheumatoid Arthritis》；Med Sci Monit. 2017 Mar 10;23:1232-1241. doi: 10.12659/msm.902454.

30.Qing Luo#, Lulu Zeng#, Hanying  Mei, Huang, Zikun Huang*,Zhongqin Luo, Jianqing Ye, Xue Li, Yang Guo, Junming Li*；《PD-L1-expressing neutrophils as a novel indicator to assess disease activity of rheumatoid arthritis》；INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE.2017;10(5):7716-7724.

31.Zikun Huang#, Rigu Su#, Zhen Deng, Jianqing Xu, Yiping Peng, Qing Luo*, Junming Li *；《Identification of differentially expressed circular RNAs in human monocyte derived macrophages response to Mycobacterium tuberculosis infection》；Sci Rep. 2017 Oct 20;7(1):13673. doi: 10.1038/s41598-017-13885-0.

32.罗清, 姚芳苡, 邓桢, 苏日古, 廖岚 ,黄自坤*.LPS 诱导的小鼠腹腔巨噬细胞炎症反应中环状RNA表达谱变化分析.中华微生物学和免疫学杂志,2017,37(6):405-411.

33.黄自坤, 李雪, 邓桢, 罗忠勤, 鞠北华, 罗清*.类风湿关节炎患者外周血 CD4+ T 和 CD8+ T细胞TIGIT的表达和意义.中华微生物学和免疫学杂志,2017, 37(5):325-332.

34.黄自坤, 罗忠勤, 李雪, 罗清*.系统性红斑狼疮患者外周血CD4+T细胞TIGIT的表达和意义.免疫学杂志,2017, 33(6):512-518.

35.黄自坤, 李雪, 鞠北华, 罗清*.类风湿关节炎患者外周血T 细胞PD1 表达的分析和意义.安徽医科大学学报,2017, 52(12):1854-1859

36. 姚芳苡, 黄自坤, 李雪, 叶建青, 罗清*.系统性红斑狼疮患者外周血中性粒细胞PD-L1表达和临床意义.安徽医科大学学报,2017, 52(2):740-745.

37.Qing Luo, Zikun Huang, Jianqing Ye, Yating Deng, Le Fang, Xue Li, Yang Guo, Hong Jiang, Beihua Ju, Qingshui Huang, Junming Li*； 《PD-L1-expressing neutrophils as a novel indicator to assess disease activity and severity of systemic lupus erythematosus》；Arthritis Res Ther. 2016 Feb 11;18:47. doi: 10.1186/s13075-016-0942-0.

38.Zikun Huang#, Qing Luo#, Yang Guo, Jie Chen, Guoliang Xiong, Yiping Peng, Jianqing Ye, Junming Li ；《Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro》；PLoS One. 2015 Jun 19;10(6):e0129744. doi: 10.1371/journal.pone.0129744.

主持的科研项目：

1.2018.8-2021.8. 江西省自然科学基金（20181BBG70013），“血浆环状RNA(circRNA)作为系统性红斑狼疮筛查分子标志物的研究”，20万

2. 2017.1-2019.12. 江西省自然科学基金（20171BAB205113）,“Tfh细胞表面负性共刺激分子TIGIT在SLE发生和发展中的作用及其调控机制”，6万

3. 2015.1-2017.12. 江西省自然科学基金（20151BAB215031）,“中性粒细胞负性共刺激分子PD-L1在RA发生和发展中的作用及其调控机制”，5万

2. 2014.1-2017.12. 国家自然科学基金（81360459）,“Tfh细胞表面负性共刺激分子TIGIT在SLE发生和发展中的作用及其调控机制”，45万