Personal Information

Name: Fankun Zhou

Position/Title: Professor, Doctoral Supervisor

Department: Occupational and Environmental Health

I. Research Directions

Research Focus: Environmental Pollution and Health, Environmental Toxicology

Email: zhoufankun@ncu.edu.cn

Office Phone: 0791-86362283

II. Representative Achievements

Publications, Monographs, and Patents:

1.Zhou F, Yin G, Gao Y, Ouyang L, Liu S, Jia Q, Yu H, Zha Z, Wang K, Xie J, Fan Y, Shao L, Feng C, Fan G. Insights into cognitive deficits caused by low-dose toxic heavy metal mixtures and their remediation through a postnatal enriched environment in rats. J Hazard Mater. 2020; 388: 122081.

2.Zhou F, Du G, Xie J, Gu J, Jia Q, Fan Y, Yu H, Zha Z, Wang K, Ouyang L, Shao L, Feng C, Fan G. RyRs mediate lead-induced neurodegenerative disorders through calcium signaling pathways. Sci Total Environ. 2020; 701:134901.

3.Zhou F, Yin G, Gao Y, Liu D, Xie J, Ouyang L, Fan Y, Yu H, Zha Z, Wang K, Shao L, Feng C, Fan G. Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures. Environ Int. 2019; 133: 105192.

4.Zhou F, Xie J, Zhang S, Yin G, Gao Y, Zhang Y, Bo D, Li Z, Liu S, Feng C, Fan G. Lead, cadmium, arsenic, and mercury combined exposure disrupted synaptic homeostasis through activating the Snk-SPAR pathway. Ecotoxicol Environ Saf. 2018; 163: 674-684.

5.Zhou F, Wu F, Zou S, Chen Y, Feng C, Fan G. Dietary, Nutrient Patterns and Blood Essential Elements in Chinese Children with ADHD. Nutrients. 2016; 8(6): 352.

6.Zhou F, Chen Y, Fan G, Feng C, Du G, Zhu G, Li Y, Jiao H, Guan L, Wang Z. Lead-induced Iron Overload and Attenuated Effects of Ferroportin 1 Overexpression in PC12 Cells. Toxicol In Vitro. 2014; 28(8):1339-1348.

7.Feng C, Liu S (Co-first author), Zhou F (Co-first author), Gao Y, Li Y, Du G, Chen Y, Jiao H, Feng J, Zhang Y, Bo D, Li Z, Fan G. Oxidative Stress in the Neurodegenerating Brain Following Lifetime Exposure to Lead in Rats: Changes in Lifespan Profiles. Toxicology. 2019; 411: 101-109.

8.Feng C, Gu J, Zhou F (Co-first author), Li J (Co-first author), Zhu G (Co-first author), Guan L, Liu H, Du G, Feng J, Liu D, Zhang S, Fan G. The effect of lead exposure on expression of SIRT1 in the rat hippocampus. Environ Toxicol Pharmacol. 2016; 44: 84-92.

9.Li Zongguang, Zhou Fankun, Yin Guangming, Gao Yanyan, Jiang Xin, Liu Sisi, Zhang Yuanyuan, Bo Dandan, Xie Jie, Jia Qiyue, Feng Jiangao, Feng Chang, Fan Guangqin. Experimental study on hippocampal neuronal cell injury in rats induced by combined exposure to low-dose mercury, lead, and cadmium. Chinese Journal of Preventive Medicine, 2018, 52(10): 976-982. (in Chinese)

10.Environmental Mercury and Arsenic Pollution and Health, edited by Zhang Aihua and Feng Xinbin. Hubei Science and Technology Press, December 2019, ISBN 978-7-5706-0720-4. (Contributor and Editorial Secretary)

11.Complete Book of Chemical Toxicity, edited by Jin Taiyi and Wang Zubing. Shanghai Scientific and Technological Literature Press, June 2020, ISBN 978-7-5439-7944-4. (Contributor)

12.Fan Guangqin, Gao Yanyan, Zhou Fankun, Tian Yue, Feng Chang, Yin Guangming, Xie Jie. An environmentally enriched training cage for laboratory animals. Utility Model Patent No. ZL201721153457.1, China National Intellectual Property Administration, authorized May 22, 2018.

III. Representative Research Projects (Principal Investigator)

1.2020.1-2022.12: National Natural Science Foundation for Young Scientists (81903360), Molecular mechanism of CIB1 regulating ubiquitination/phosphorylation dual pathways in dendritic spine dynamics underlying neurobehavioral abnormalities induced by low-dose combined heavy metal exposure. ¥210,000.

2.2020.1-2022.12: Jiangxi Provincial High-level Talent Introduction and Entrepreneurship Program “Thousand Talents Plan” (first batch), High-end Scientific and Technological Innovation Talent (Youth) Project. ¥1,000,000.

3.2019.7-2022.6: Jiangxi Provincial Natural Science Foundation for Young Scholars (20192BAB215048), Intervention effects and molecular mechanisms of small-molecule polyphenols on neurodevelopmental disorders induced by heavy metal pollution. ¥60,000.

4.2019.1-2021.12: Young Faculty Research Cultivation Fund Project of the Medical Department, Nanchang University (PY201807), Role and mechanism of plant polyphenols in improving heavy metal-induced cognitive impairment. ¥50,000.