Personal Information

Name: Dalei Zhang

Email: zhangdalei@ncu.edu.cn

Department: School of Public Health

Title: Professor

I. Research Directions

(1) Research Focus: Reproductive Health

(2) Main Research Areas: Reproductive Physiology and Pathology; Environmental Toxicology and Health

II. Academic Profile

·Jul 2007: Received Ph.D. from Zhejiang University

·Jul 2007 – Nov 2011: Lecturer, Nanchang University

·Dec 2011 – Nov 2016: Associate Professor, Nanchang University

·Sep 2018 – Sep 2019: Visiting Scholar, Cornell University, USA

·Dec 2016 – Present: Professor and Doctoral Supervisor, Nanchang University

III.Academic Affiliations

·Deputy Director, Jiangxi Key Laboratory of Disease Prevention and Public Health

·Standing Council Member, Jiangxi Physiological Society

·Senior Member, Chinese Society of Toxicology 

·Committee Member, Health Management Professional Committee, Jiangxi Maternal and Child Health & Eugenics Association

·Editorial Board Member, Journal of Nanchang University (Medical Sciences)and Practical Clinical Medicine

IV. Representative Publications

1.Exposure to nanoplastics induces mitochondrial impairment and cytomembrane destruction in Leydig cells. Ecotoxicology and Environmental Safety. 2023, 255, 114796: 1-12. (Corresponding Author)

2.Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring. Food and Chemical Toxicology. 2022, 160, 112803: 1-10. (Corresponding Author)

3.Bisphenol S exposure induces cytotoxicity in mouse Leydig cells. Food and Chemical Toxicology. 2022, 160, 112805: 1-9. (Corresponding Author)

4.PFOA evokes extracellular Ca⟡⁺ influx and compromises progesterone-induced response in human sperm. Chemosphere. 2020, 241, 125074: 1-8. (Corresponding Author)

5.Perfluorooctanoic acid induces cytotoxicity in spermatogonial GC-1 cells. Chemosphere. 2020, 260, 127545: 1-8. (Corresponding Author)

V. Representative Research Projects

1.National Natural Science Foundation of China: “Study on the toxic effects and mechanisms of nanoplastics on Leydig cells via mitochondrial stress-ferroptosis pathway.” Jan 2024 – Dec 2027, No. 82171606, Principal Investigator.

2.National Natural Science Foundation of China: “Study on the toxic effects and mechanisms of PFASs on sperm based on the CatSper-Ca⟡⁺-mitochondrial axis.” Jan 2022 – Dec 2025, No. 82171606, Principal Investigator.

3.National Natural Science Foundation of China: “Investigating the mechanism of PFOA/PFOS-induced hepatotoxicity via the Nrf2 signaling pathway and the intervention effect of naringin.” Jan 2019 – Dec 2022, No. 81860112, Principal Investigator.

4.National Natural Science Foundation of China: “Mechanism of PFOA-induced testicular germ cell toxicity and the regulatory role of Nrf2.” Jan 2016 – Dec 2019, No. 81560248, Principal Investigator.

5.National Natural Science Foundation of China: “Study on the regulation of environmental endocrine disruptor-induced spermatogonial cytotoxicity by the Nrf2-ARE system.” Jan 2011 – Dec 2013, No. 81060056, Principal Investigator.