Personal Information

Name: Chang Feng

Email: fengchang@ncu.edu.cn

Department: School of Public Health, Medical Department, Nanchang University

Title: Professor

I. Research Directions

(1) Research Focus: Health Effects, Mechanisms, and Interventions of Environmental Heavy Metal Exposure

(2) Main Research Area: Heavy Metal Neurotoxicity

II.  Academic Profile

·Dec 2011 – Present: Professor, School of Public Health, Nanchang University

·Nov 2004 – Nov 2011: Associate Professor, School of Public Health, Nanchang University

·Sep 1998 – Oct 2004: Lecturer, Department of Preventive Medicine, Jiangxi Medical College

·Sep 1998 – Jul 2003: M.Med. (Pharmacology), Jiangxi Medical College

·Jul 1992 – Aug 1998: Teaching Assistant, Department of Preventive Medicine, Jiangxi Medical College

·Sep 1987 – Jun 1992: B.Med. (Preventive Medicine), Jiangxi Medical College

III. Academic Affiliations

Committee Member, Immunotoxicology Committee, Chinese Society of Toxicology

Committee Member, Public Health Education Branch, Jiangxi Preventive Medicine Association

IV.  Honors and Awards

Health Hazard Mechanisms of Environmental Lead Pollution and Their Prevention & Control Applications. Jiangxi Provincial People's Government, Second Prize for Science and Technology Progress, 2021.

Instructor for the team winning the Gold Medal (Third Place) in the Preventive Medicine Track Finals of the "10th Chinese College Students Medical Technology Skills Competition", 2021.

Third Prize, Enterprise Designated Category (ZZJY202106310), 6th National Higher Education Institution Faculty Self-Made Experimental Teaching Instrument and Equipment Innovation Competition (part of National College Faculty Innovation Contest), 2021.

Jiangxi Provincial Excellent Master's Thesis Supervisor Award: "Effects of Low-Dose Combined Heavy Metal Exposure on Neuronal Synapses and Their Regulatory Proteins in Rats." Jiangxi Provincial Department of Education & Jiangxi Provincial People's Government Academic Degrees Committee, 2023.

Jiangxi Provincial Excellent Master's Thesis Supervisor Award: "The Role of RyRs in Synaptic Plasticity Damage in the Hippocampal CA1 Region of Rats Induced by Lead." Jiangxi Provincial Department of Education & Jiangxi Provincial People's Government Academic Degrees Committee, 2019.

Jiangxi Provincial Higher Education Institution Scientific and Technological Achievement Award: "The Role of Neuronal DMT1 and FP1 in Lead-Induced Neurodegenerative Changes." Jiangxi Provincial Department of Education, 2013.

Jiangxi Provincial Higher Education Institution Scientific and Technological Achievement Award: "Regulatory Role of Methionine Choline in Antagonizing LTP Signal Transduction Impairment in Learning and Memory Caused by Environmental Heavy Metal Lead." Jiangxi Provincial Department of Education, 2011.

Third Prize, Enterprise Designated Category (ZZJY202106310), 6th National Higher Education Institution Faculty Self-Made Experimental Teaching Instrument and Equipment Innovation Competition (part of National College Faculty Innovation Contest), 2021.

Jiangxi Provincial Excellent Master's Thesis Supervisor Award: "Effects of Low-Dose Combined Heavy Metal Exposure on Neuronal Synapses and Their Regulatory Proteins in Rats." Jiangxi Provincial Department of Education & Jiangxi Provincial People's Government Academic Degrees Committee, 2023.

V.  Representative Publications

Feng, Chang; Liu, Sisi; Zhou, Fankun; Gao, Yanyan; Li, Yanshu; Du, Guihua; Chen, Ying; Jiao, Huan; Feng, Jiangao; Zhang, Yuanyuan; Bo, Dandan; Li, Zongguang; Fan, Guangqin; Oxidative Stress in the Neurodegenerative Brain Following Lifetime Exposure to Lead in Rats: Changes in Lifespan Profiles. Toxicology, 2019, 411: 101-109.

Feng, Chang; Gu, Junwang; Zhou, Fankun; Li, Jiaoyang; Zhu, Gaochun; Guan, Linfu; Liu, Haizhen; Du, Guihua; Feng, Jiangao; Liu, Dong; Zhang, Shuyun; Fan, Guangqin; The effect of lead exposure on expression of SIRT1 in the rat hippocampus. Environmental Toxicology and Pharmacology, 2016, 44: 84-92.

Song Jingyu; Li Yanshu; Chen Ying; Jiao Huan; Feng Chang; Effects of lead exposure on the expression of APP and tau protein in the hippocampus of rats. Chinese Journal of Public Health, 2016, 32(6): 778-781. (Corresponding Author)

Zhu, Gaochun; Fan, Guangqin; Feng, Chang; Li, Yanshu; Chen, Ying; Zhou, Fankun; Du, Guihua; Jiao, Huan; Liu, Zhenghua; Xiao, Xinlan; Lin, Fen; Yan, Ji; The effect of lead exposure on brain iron homeostasis and the expression of DMT1/FP1 in the brain in developing and aged rats. Toxicology Letters, 2013, 216: 108-123. (Co-first Author)

VI.  Representative Research Projects

National Natural Science Foundation of China (81760599): Role of MEF2, an SIRT1/ERK Allosterically Modified Synaptic Growth Controller, in the Molecular Mechanism of Learning and Memory Impairment Induced by Lead Exposure. Jan 1, 2018 – Dec 31, 2021. (Principal Investigator)

Jiangxi Provincial Natural Science Foundation (20142BAB205019): Role of Ferroportin 1 in Alzheimer's Disease-like Changes Induced by Lead Exposure. Jan 2015 – Dec 2017. (Principal Investigator)