Team Leader: Prof. Xianglei Cheng

Email: chengxl@ncu.edu.cn

 Prof. Xianglei Cheng serves as a member of the National Teaching Material Review Committee for Health Inspection and Quarantine programs (2nd edition) and is the coordinator of a Jiangxi Provincial High-Quality Online Open Course.

Research Focus

The team conducts research on the detection, characterization, and health risk assessment of environmental and food-related hazard factors, integrating analytical chemistry, biosensing technologies, and public health risk evaluation. Major research themes include:

—   Development of high-sensitivity analytical methods for toxic and carcinogenic compounds in food and the environment

—   Mechanistic studies of chemiluminescence and nanomaterial-based sensing systems

—   Detection and transformation mechanisms of nitrosamines, pesticides, antibiotics, and emerging contaminants

—   Health risk evaluation of heavy metals, selenium, and environmental pollutants

Selected Research Projects

Prof. Cheng has led multiple projects funded by the National Natural Science Foundation of China (NSFC) and provincial funding agencies. Representative research projects include:

—   Mechanism of GPX4-mediated STING Activation in Hexavalent Chromium-induced Lung Carcinogenesis based on Ferroptosis (NSFC, 2025-2028)

—   Study on a New Method and Mechanism for Constructing Nitrosamines and Their Precursors via Fluorescence Activation by UV Photolysis Intermediates (NSFC, 2024-2027)

—   Luminescence Mechanism of Carbon Dots Targeting Nitrosamine Degradation Intermediates and Development of a Novel HPLC-CL Method (NSFC, 2022-2025)

—   Study on the Mechanism and a Novel Chemiluminescence Method for Periodate-Tetracyclines Mediated by Reaction Medium (NSFC, 2020-2023)

—   A Novel Ultrasensitive Chemiluminescence System for PPCPs Mediated by Reactive Oxygen Species and Its Coupling with HPLC (NSFC, 2018-2021)

—   Mechanistic Study on the Diversity of Chemiluminescence Behaviors between Fluoroquinolones and ONOOH (NSFC, 2013-2016)

—   Research on Rapid Visual Imaging Detection of Fluoroquinolone Residues (NSFC, 2013-2016)

—   Bioavailability of Selenium in Low Hilly Red Soil and Its Potential Health Risks (NSFC, 2012-2015)

Selected Publications

—   Wei Lijun, Zhou Bixiao, Cai Mengdie, Wang Xinyu, Zhang Guowen, Xianglei Cheng. Amide carbon quantum dots as chemiluminescent probes for the real-time quantitative detection of the carcinogen ethylene thiourea and its homologs in vegetables. Food Chemistry, 2025, 484, 144372.

—   Cai Mengdie , Wang Xinyu, Lu Kun, Zhou Bixiao, Lijun Wei, Xianglei Cheng. Development of a novelly selective HPLC-chemiluminescence method by targeting degradation intermediates of nitroimidazoles and its application in animal food products. Food Chemistry: X, 2025, 25, 102205.

—   Wei Lijun, Cai Mengdie, Zhou Bixiao, Yuan Ping, Zhang Guowen, Cheng Xianglei. Novel sulphur-selective method for simultaneous determination of thiram and asomate based on carbon dots and its application in fruits. Food Chemistry: X, 2024, 24, 101879.

—   Wei Lijun, Gan Weimin, Cai Mengdie, Cai Hongping , Zhang Guowen, Cheng Xianglei. Development of a novel HPLC-CDCL method utilizing nitrogen-doped carbon dots for sensitive and selective detection of dithiocarbamate pesticides in tea. Food Chem., 2024. 458, 140237.

—   Ding Zhiqin, Cai Mengdie, Gan Weimin, Yuan Ping, Wei Lijun, Cheng Xianglei. Studies on a novel method for the determination of nitrosamines in food by HPLC-UV-FLD coupling with terbium-doped carbon dots. Food Chemistry, 2023, 405, 134894.

—   Cai Mengdie, Gan Weimin, Ding Zhiqin, Cai Hongping, Wei Lijun, Cheng Xianglei. Studies on reaction mechanisms and distinct chemiluminescence from cyanoimino neonicotinoids triggered by peroxymonosulfate in advanced oxidation processes. Chinese Chemical Letters, 2023, 34(3): 107554.

—   Wang Yuexuan; Wang Xiangjun; Long Changmao; Zhang Zhihong; Cheng Xianglei; Zhang Baojun; Quantitative health risk evaluation of heavy metal contamination in urban green spaces: a case study of Nanchang's metropolitan ore, Environmental Geochemistry and Health, 2025, 47(6): 196.

—   Wang Xiangjun; Wang Yuexuan; Xu Minghuan; Cheng Xianglei; Long Changmao; Wei Lijun; Zhang Baojun; Temporal and spatial variations of soil Se in China over the past half century and its influencing factors, Environmental Geochemistry and Health, 2025, 47(2): 55.

—   Hu Liang; Wang Xianglian; Wu Daishe; Zhang Baojun; Fan Houbao; Shen Fangfang; Liao Yingchun; Huang Xueping; Gao Guiqing ; Effects of organic selenium on absorption and bioaccessibility of arsenic in radish under arsenic stress, Food Chemistry, 2021, 344: 128614.

—   Wang Xianglian; Zhang Baojun; Wu Daishe; Hu Liang; Huang Ting; Gao Guiqing; Huang Shan; Wu Shan ; Chemical forms governing Cd tolerance and detoxification in duckweed (Landoltia punctata), Ecotoxicology and Environmental Safety, 2021, 207: 111553.

—   Long C, Wang X, Wang D, Chen Y, Zhang B. Deciphering the impact of heavy metal mixed exposure on lipid metabolism using three statistical models. Environ Geochem Health. 2024, 47(1): 20.

—   Long C, Su Z, Hu G, Zhang Q, Zhang Y, Chen T, Hong S, Su L, Jia G. Potential mechanisms of lung injury and repair after hexavalent chromium [Cr(VI)] aerosol whole-body dynamic exposure. Chemosphere. 2024,349:140918.

—   Long C, Hu G, Zheng P, Chen T, Su Z, Zhang Y, Ding C, Peng F, Yu S, Wang T, Jia G. Analysis of serum metabolome of workers occupationally exposed to hexavalent chromium: A preliminary study. Toxicol Lett. 2021, 349: 92-100.

Team Members

Baojun Zhang

Changmao Long

Hongping Cai

Lijun Wei

Ping Yuan